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research Case Report: Secondary syphilitic alopecia following non-penetrative sexual contact: a case of initial misdiagnosis

April 2026 in “Frontiers in Medicine”

This case study reports a 26-year-old male with secondary syphilitic alopecia misdiagnosed as alopecia areata, likely contracted through non-penetrative sexual contact. Effective treatment with intramuscular benzathine penicillin G led to complete hair regrowth within three months.

research Essential syphilitic alopecia: Non-scarring alopecia in 21-year-old man

January 2021 in “Our Dermatology Online”

This case report discusses alopecia syphilitica in a young Belgian man, notes that hair loss was his only symptom, and highlights the improvement following penicillin treatment.

research Moth-eaten essential syphilitic alopecia

3 citations , July 2014 in “QJM”

This case report discusses a 35-year-old man with progressive alopecia areata who did not respond to minoxidil treatment but offers no new clinical trial results.

research Moth-eaten alopecia and beyond: Syphilitic alopecia - Revisited

1 citations , July 2024 in “Indian Journal of Sexually Transmitted Diseases and AIDS”

In this study, a 38-year-old male with syphilis-related mixed pattern alopecia showed marked hair regrowth and resolution of postauricular lymphadenopathy after treatment with benzathine penicillin, suggesting that lymph node and hair examinations, along with trichoscopy, can aid in the diagnosis of alopecia syphilitica.

research A Neonate with Unexplained Hair Loss

1 citations , May 2019 in “The Journal of Pediatrics”

The baby's hair loss was due to congenital syphilis, which was treated with penicillin.

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7 / 800 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Do alopecia areata patches scar? And is there evidence for peptides? Alopecia areata patches usually still have living follicles and often regrow. One small trial of a cosmetic peptide lotion reported improvement, but no peptide is an approved treatment; see a dermatologist.

learn PP405

Can PP405 help bald patches caused by stress? PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Baicapil

Patchy hair loss or alopecia areata: is there any evidence for Baicapil? There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts; none of it involved people with autoimmune patchy hair loss.

learn Scalp Micropigmentation

scalp tattoos to mimic the appearance of light stubble

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Small, short trials suggest topical vitamin D analogues such as calcipotriol may help some people with mild patchy alopecia areata. There is no trial evidence that they help pattern hair loss.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 has been studied only in men with androgenetic alopecia, in two Phase 1 studies and one 16-week Phase 2 trial. There is no research on it in women or in any other type of hair loss.

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Community Join

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community Daily Mail article - How I REVERSED my balding. My barber called my thick head of hair a 'miracle'... this is exactly how I did it:

in Finasteride/Dutasteride 1 upvotes 1 year ago

Finasteride and a hair transplant were used to reverse hair loss, leading to thicker hair and increased confidence. The user received compliments on their improved appearance.

community Random bald spot suddenly appeared

212 upvotes 1 month ago

A user noticed a sudden bald spot and others suggested it might be alopecia areata, often stress-induced, recommending seeing a dermatologist for steroid injections. Topical minoxidil was mentioned as a successful treatment by one user.

community What hair loss pattern is this?

in General 157 upvotes 9 months ago

The user noticed small circular hairless spots after a buzz cut and has been using finasteride, dutasteride, and oral minoxidil for hair loss. They are experiencing continuous shedding and thinning, and it is suggested they consult a dermatologist for a scalp examination and possible biopsy to determine if it's alopecia areata or androgenetic alopecia.

community Diffuse thinner asking for help. Density patches, shedding, seb derm and itching

in Basic Questions 175 upvotes 2 months ago

The user is experiencing hair loss and has been using treatments like minoxidil, finasteride, and ciclopirox olamine. Despite these treatments, they are concerned about increased shedding, dandruff, and possible additional hair loss conditions.

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