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This article addresses diffuse pattern essential syphilitic alopecia as an unusual form of secondary syphilis but provides no new clinical findings.

This case study reports a 26-year-old male with secondary syphilitic alopecia misdiagnosed as alopecia areata, likely contracted through non-penetrative sexual contact. Effective treatment with intramuscular benzathine penicillin G led to complete hair regrowth within three months.

The authors concluded that trichoscopic examination can be useful for diagnosing syphilitic alopecia in patients with idiopathic alopecia, though the findings are nonspecific and further studies are needed.

In this study, a 38-year-old male with syphilis-related mixed pattern alopecia showed marked hair regrowth and resolution of postauricular lymphadenopathy after treatment with benzathine penicillin, suggesting that lymph node and hair examinations, along with trichoscopy, can aid in the diagnosis of alopecia syphilitica.

This case report discusses alopecia syphilitica in a young Belgian man, notes that hair loss was his only symptom, and highlights the improvement following penicillin treatment.