Moth-Eaten Alopecia in Secondary Syphilis

A 24-year-old male presented with symptoms indicative of secondary syphilis, including a faint rash, generalized lymphadenopathy, and "moth-eaten alopecia." His VDRL and TPHA tests were strongly positive, and a skin biopsy confirmed secondary syphilis as the cause of the alopecia. The patient was treated with a single dose of benzathine penicillin, resulting in the resolution of the rash and lymphadenopathy. The alopecia is expected to resolve as it is non-scarring. This case highlights the importance of recognizing "moth-eaten alopecia" as a clinical sign of secondary syphilis.