A Retrospective Study on the Safety of Systemic Minoxidil for Hair Loss in the Older Population

    Blythe N. Ke, Damkerng Pathomvanich
    Studysummary This study investigated adverse events from low-dose systemic minoxidil in an older population with hair loss and found that 19% experienced mainly facial and body hypertrichosis, managed with interventions like dose reduction and diuretics; no serious adverse events occurred.
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    Research cited in this study 11

    1. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    2. A Systematic Review and Meta-Analysis of Randomized Controlled Trials of United States Food and Drug Administration-Approved, Home-Use, Low-Level Light/Laser Therapy Devices for Pattern Hair Loss: Device Design and Technology PubMed · 2021
    3. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    4. Androgenetic Alopecia: Update on Etiology Dermatological reviews · 2021
    5. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    6. Coming Full Circle (Almost): Low Dose Oral Minoxidil for Alopecia Journal of The American Academy of Dermatology · 2021
    7. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    8. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    9. Low-Dose Oral Minoxidil as Treatment for Non-Scarring Alopecia: A Systematic Review International Journal of Dermatology · 2020
    10. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    11. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011

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    3. 5% Minoxidil: Treatment for Female Pattern Hair Loss PubMed · 2015
    4. Effectiveness of Once Daily 5% Minoxidil Topical Foam in the Treatment of Women with Thinning Hair Due to Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2015
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    6. Androgenetic Alopecia in Adolescents PubMed · 2003
    7. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    8. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    9. The Use of Minoxidil to Prevent Alopecia During Chemotherapy for Gynecologic Malignancies PubMed · 1991