Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent

    October 2018 in “ Dermatologic Therapy ”
    Jill Chitalia, Rachita Dhurat, Andy Goren … Torello Lotti
    Studysummary In this study of Indian patients with pattern hair loss, 40.8% showed low sulfotransferase enzyme activity in hair follicles, with a higher prevalence of low activity in men compared to women.
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    Research cited in this study 9

    1. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    2. Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia Dermatologic Therapy · 2014
    3. Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2013
    4. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    5. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    6. Androgenetic Alopecia in the Female Archives of Dermatology · 1994
    7. Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women International Journal of Dermatology · 1993
    8. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990
    9. Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase Biochemical Pharmacology · 1990

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    3. Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent Dermatologic Therapy · 2018
    4. Understanding and Management of Female Pattern Alopecia Facial Plastic Surgery · 2008