Epidermal Deletion of Rac1 Causes Stem Cell Depletion, Irrespective of Whether Deletion Occurs During Embryogenesis or Adulthood

February 2007 in “ Journal of Investigative Dermatology ”

Salvador Aznar Benitah, Fiona M. Watt

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research Rac1 Is Crucial for Hair Follicle Integrity but Not Essential for Epidermis Maintenance

139 citations , August 2006 in “Molecular and Cellular Biology”

Rac1 is vital for hair follicle health but not needed for skin maintenance.

research Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis

421 citations , September 2003 in “Development”

Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.

research Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment

182 citations , May 2003 in “Development”

Myc activation reduces skin stem cells by affecting cell adhesion.