Vδ1+ T-Cells Are Stress-Sentinels in Human Skin and Are Implicated in Alopecia Areata Pathogenesis

    August 2016 in “ Journal of Investigative Dermatology ”
    Youhei Uchida, Jennifer Gherardini, Majid Alam, Aviad Keren, Akiko Arakawa, Alfredo Rossi, Amos Gilhar, Takuro Kanekura, Marta Bertolini, Ralf Paus
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

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    Studysummary This study suggests that human dermal Vδ1+ γδ T-cells may contribute to alopecia areata pathogenesis by targeting stressed scalp hair follicles and inducing immune privilege collapse.
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