A Convenient Synthesis Of (16S,20S)-3β-Hydroxy-5α-Pregnane-20,16-Carbolactam And Its N-Alkyl Derivatives

    May 2020 in “ Molecules ”
    Agnieszka Wojtkielewicz, Damian Pawelski, Przemysław Bazydło … Jacek W. Morzycki
    Studysummary This paper describes the synthesis of (16S,20S)-3β-hydroxy-5α-pregnane-20,16-carbolactam from tigogenin without presenting new experimental results.
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    Research cited in this study 3

    1. Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia Annals of Dermatology · 2016
    2. Synthesis, Antiproliferative, Acute Toxicity and Assessment of Antiandrogenic Activities of Some Newly Synthesized Steroidal Lactams European Journal of Medicinal Chemistry · 2010
    3. The Clinical Development of a 5α-Reductase Inhibitor, Finasteride The Journal of Steroid Biochemistry and Molecular Biology · 1990