Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
April 2010
in “
Development
”
hair follicle stem cell niche bulge cells hair germ cells hematopoietic stem cells Bmi1-positive cells Lgr5+ crypt base columnar cells astrocytes lineage tracing Cre-recombinase-mediated lineage tracing niche environment stem cell identity stem cell states hair follicle stem cells hair growth cells blood stem cells intestinal stem cells brain cells Cre-recombinase tracing stem cell environment
Studysummary This article discusses the bi-compartmental organization of hair follicle stem cell niches for balancing stem cell cycling and organ growth and proposes similar structures may exist in other adult stem cell niches but reports no new experimental results.
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