TLDR Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
This systematic review and meta-analysis compared the efficacy and safety of dutasteride and finasteride in treating men with androgenetic alopecia (AGA). Three randomized controlled trials (RCTs) were included in the study, which analyzed the mean change in total hair count, investigator's assessment of global photographs, panel global photographic assessment, and subjects' assessment. The results showed that dutasteride was more effective than finasteride in increasing total hair count and improving the investigator's and panel global photographic assessments for the vertex and frontal views. However, there was no significant difference in subjects' assessment between the two drugs. In terms of safety, dutasteride was associated with a higher risk of altered libido compared to finasteride.View this study on dovepress.com →
Androgens may block hair growth signals, targeting this could treat hair loss.
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.
Hair loss requires customized treatments based on its various causes and types.
Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.
Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.
Finasteride 1 mg effectively and safely increases hair growth in Japanese men with hair loss.
Male pattern baldness involves hormones and cell signals affecting hair growth.
Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
Smoking linked to hair loss in Asian men.
Dutasteride more effective for hair growth, but has more side effects than finasteride.
Finasteride increases hair weight and count in men with hair loss, with best results after four years.
Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.
In Bishan, Singapore, 63% of men have androgenetic alopecia, a type of hair loss, with rates increasing with age and more common in Indians than Chinese.
Hair loss in men is common, treatable, but not curable.
Genetics and hormones cause hair loss; finasteride treats it safely.
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.
Hair loss can cause low self-esteem, anxiety, and depression in men.
Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.