Platelet-Rich Plasma Improves Caspase-3 of Skin Graft Treated with Tilapia Mozambique Bio-Dressing

    January 2025 in “ Open Veterinary Journal ”
    Etriwati Etriwati, Abellisa Abellisa, Teuku Ferasyi, Sugito Sugito, Amiruddin Amiruddin, Rumi Zamzami, Erwin Erwin
    TLDR PRP with TM bio-dressing improves skin graft healing in cats.
    This study evaluated the effects of Platelet-rich Plasma (PRP) and Tilapia Mozambique (TM) bio-dressing on auto skin graft (ASG) healing in 9 male cats. The cats were divided into three groups: a control group with moist dressing, a group treated with only TM bio-dressing, and a group treated with both PRP and TM bio-dressing. Results showed that the group receiving both PRP and TM bio-dressing exhibited improved epithelial tissue thickness, hair follicle, sweat gland, sebaceous gland development, and neovascularization. Additionally, this group had less dense collagen and a broader distribution of caspase-3 positive cells, indicating enhanced healing. The study concludes that PRP combined with TM bio-dressing is more effective for ASG in cats.
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      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

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      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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