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Glossary Sweat Glands

small skin structures producing sweat for temperature regulation

Sweat glands, also known as sudoriferous glands, are small tubular structures in the skin responsible for producing sweat. They play a crucial role in regulating body temperature and excreting waste products. There are two main types: eccrine glands, which are found all over the body and primarily help with cooling, and apocrine glands, which are located in specific areas like the armpits and groin and are associated with body odor.

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research Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

265 citations , July 2012 in “Cell”

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

research Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis

103 citations , April 2010 in “Journal of Investigative Dermatology”

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

research Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors

73 citations , November 2001 in “Journal of Investigative Dermatology Symposium Proceedings”

This review examines histochemical and immunohistochemical markers to differentiate apocrine and eccrine sweat glands, highlighting their distinct markers, though it reports no new clinical findings.

research Using bioprinting and spheroid culture to create a skin model with sweat glands and hair follicles

65 citations , January 2021 in “Burns & Trauma”

This study developed an in vitro model revealing that hair follicle spheroids enhanced both sweat gland and hair follicle differentiation within bioprinted scaffolds, while microenvironmental cues supported persistent regeneration.

research Involvement of Wnt, Eda and Shh at defined stages of sweat gland development

55 citations , September 2014 in “Development”

In this study, mouse sweat gland development relied on a regulatory sequence initiated by Wnt/β-catenin signaling, and disruptions in Wnt, Eda, or Shh pathways led to distinct developmental failures.

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community I’ve catch my hair loss early and I’m glad I took the measures to prevent it

in Chat 1 year ago

The conversation discusses a 17-year-old using finasteride to address early hair thinning, expressing pride in taking action to prevent hair loss. The user emphasizes the importance of starting treatment early and shares experiences with the hair loss community.

community Not sure if it's in my head or not but I swear Nizoral 2% has made my hair thicker

in Ketoconazole 45 upvotes 1 year ago

The user noticed thicker hair and reduced dandruff after using Nizoral 2% (ketoconazole) every few days, alongside topical minoxidil 5% for over a year. They plan to reduce Nizoral use to once a week to avoid scalp irritation.

community Hot weather causing hair shedding?

3 upvotes 9 months ago

Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community 1 year 3 months finasteride and back to the drawing board..

5 upvotes 4 years ago

The user has been using finasteride for over a year, which improved their hairline but not the crown area. They are considering alternatives like hair fibers, derma stamping, or possibly minoxidil, while avoiding topicals due to their work environment.

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