Effects of Platelet-Rich Plasma on Hair Growth Using Artificial Intelligence-Based Trichoscopy and Ki67+ Keratinocytes Analysis: A Randomized Placebo-Controlled Trial

    July 2025 in “ Clinical Dermatology Review
    Debdeep Mitra, Murali Sundaram, Manoj Kumar, Gagandeep Kaur, Anuj Bhatnagar, Amrita Parmar, Navya Donaparthi, Pramod Kumar
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    TLDR PRP significantly boosts hair growth in androgenic alopecia patients.
    This study evaluated the effects of platelet-rich plasma (PRP) on hair growth in 35 patients with androgenic alopecia using a randomized, placebo-controlled split-scalp design. PRP was administered monthly for 3 months, and results showed a significant increase in hair density on the PRP-treated side, with an 8.4% increase after 3 months and a 19.1% increase after 6 months. The study also observed a reduction in single-hair follicular units and an increase in multiple follicular units, along with increased cell proliferation in hair follicles as indicated by Ki67+ IHC analysis. These findings suggest that PRP is a promising treatment for hair regrowth in AGA patients.
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