Determination of Proliferation and Collagen Synthesis of Human Dermal Hair Papilla Cells

The study aimed to determine the proliferation and collagen synthesis of human dermal hair papilla cells. It found that cell proliferation had a high phase on the 11th day in basal culture medium and two high phases on the 5th and 11th days in routine culture medium. Collagen synthesis did not differ among dermal hair papilla cells, dermal sheath cells, and fibroblasts, but the collagen amount was higher in fibroblast medium. This suggested different functions for these cells. The study concluded that routine culture medium was effective for cell growth and proliferation, and that dermal hair papilla and sheath cells had a lower collagen secretion ability compared to fibroblasts.