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    GlossaryDermal Papilla Cells

    specialized cells at hair follicle base crucial for hair growth

    Dermal Papilla Cells (DPCs) are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by interacting with surrounding cells to regulate the hair growth cycle. These cells are essential for the formation of new hair follicles and are a key focus in research on hair loss treatments and regenerative medicine.

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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 2 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 11 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  41 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.