Proinflammatory Event of Ozonized Olive Oil in Mice

    May 2009 in “ Ozone Science and Engineering ”
    Hiromi Kataoka, Masanori Semma, Humitoshi Sakazaki, Katsuhiko Nakamuro, Tadashi Yamamoto, Seiichi Hirota, Keiko Tazuya-Murayama, Atsushi Ichikawa
    Studysummary This study found that while ozonized olive oil inhibited swelling in a mouse model of hypersensitivity, it also induced inflammatory responses and hair loss with repeated skin application, indicating potential adverse effects.
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    The study investigated the proinflammatory effects of ozonized olive oil in mice. Researchers found that the application of ozonized olive oil led to a significant increase in inflammatory markers, indicating a proinflammatory response. This suggested that while ozonized olive oil might have been considered for therapeutic uses, its potential to induce inflammation needed to be carefully considered. The study provided insights into the biological effects of ozonized compounds and highlighted the importance of evaluating the inflammatory potential of such treatments.
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