Prenatal Hair Development: Implications for Drug Exposure Determination

January 2010 in “ Forensic science international ”

Joey Gareri, Gideon Koren

hair follicles placodes anagen phase catagen phase telogen phase ectodermal layer mesodermal layer

Studysummary This review discusses fetal hair follicle development and its importance for determining in utero drug exposure through neonatal hair, but it reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.

The document discussed the development of hair follicles during prenatal stages, highlighting the interactions between ectodermal and mesodermal layers. Hair follicle development began around the 8th week with the formation of placodes, and by the 10th week, initial hair production started. By the 20th week, the entire scalp was covered with anagen phase hair. The first hair cycle concluded with catagen/telogen phases between the 24th and 28th weeks. The study emphasized that scalp hair fibers present at birth reflected metabolic activity occurring after the 28th week of prenatal development.

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