Exploring the Potential of Herbal Drugs for the Treatment of Hair Loss

August 2021 in “ GSC biological and pharmaceutical sciences ”

Shivam A. Bartere, Lochana L. Malode, Gunjan P. Malode, Minakshee G. Nimbalwar, Chaitanya A. Gulhane, Jagdish V. Manwar, Ravindra L. Bakal

hair loss alopecia genetic predispositions environmental triggers medications nutritional deficiencies extreme stress prolonged illness medicinal plants

Studysummary This article reviews various causes of hair loss, including genetic and environmental factors, and explores different medicinal plants that may help prevent or treat hair loss. Our plain-language summary of this paper — not a Tressless recommendation.

The paper "Exploring the potential of herbal drugs for the treatment of hair loss" discusses the impact of hair loss on an individual's mental health and overall quality of life. Hair loss can be caused by various factors such as genetic predispositions, environmental triggers, exposure to chemicals, medications, nutritional deficiencies, extreme stress, or prolonged illness. The authors provide information about different types of alopecia and their causes. They also discuss various medicinal plants and their parts used in the prevention or treatment of hair loss.

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Research cited in this study

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Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

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This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

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In this study, finasteride was found to be more effective than 5% minoxidil for treating male androgenetic alopecia in Chinese patients, with combination therapy showing the greatest improvement.

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research Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness

75 citations , December 2011 in “British Journal of Dermatology”

This review discusses female pattern hair loss, its psychological impact, and available treatments but provides no new clinical findings; the authors emphasize early intervention for better outcomes.

research Development and Evaluation of Polyherbal Ointment for Hair Growth Activity

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This study observed that a polyherbal ointment containing extracts from several plants promoted significant hair growth in rats compared to using single plant extracts.

research Eclipta Alba Extract With Potential For Hair Growth Promoting Activity

121 citations , May 2009 in “Journal of Ethnopharmacology”

This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.

research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men

112 citations , October 2005 in “Mayo Clinic Proceedings”

This article reviews the clinical, psychological, and management aspects of androgenetic alopecia in men, stating that it can be effectively managed by generalist clinicians with pharmacotherapy and surgical advancements.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research The Hair Growth Promoting Effect of Asiasari Radix Extract and Its Molecular Regulation

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This study found that the extract of Asiasari radix may promote hair growth in mice by enhancing protein synthesis, cell proliferation, and growth factor expression.

research In Vivo and In Vitro Evaluation of Hair Growth Potential of Hibiscus Rosa-Sinensis Linn.

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This study found that the petroleum ether extract from the leaves of Hibiscus rosa-sinensis demonstrated more effectiveness in promoting hair growth in rats compared to the extract from its flowers.

research Psychological Features of Androgenetic Alopecia

46 citations , September 2002 in “Journal of the European Academy of Dermatology and Venereology”

In this study, depression was more common among women with androgenetic alopecia, while men showed higher levels of anxiety, aggressiveness, and a lack of adherence to treatment.

research Effect of Leaves of Ginkgo Biloba on Hair Regrowth in C3H Strain Mice

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This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.