Polycystic Ovary Syndrome Phenotypes and Metabolic Dysfunction Relationship

This study investigated the relationship between different phenotypes of polycystic ovary syndrome (PCOS) and metabolic dysfunction in 100 patients diagnosed using the Rotterdam criteria. The prevalence of metabolic syndrome (MetS) was compared across four phenotypes: A (30.3%), B (24.1%), C (15.4%), and D (36%). Although phenotype A showed higher obesity and insulin resistance, the differences between phenotypes were not statistically significant. However, MetS was significantly more prevalent in obese patients (p < 0.001), and the LH/FSH ratio was notably higher in obese individuals (p = 0.011). The study concluded that while obesity is linked to higher MetS and LH/FSH ratios, no significant differences were found among the four PCOS phenotypes.