Epidermolysis Bullosa Simplex Keratinocytes Show Disturbed Mitochondrial Positioning and Activity

    January 2020 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Alyssa Vetter, Kristin Jahn, Jamal-Eddine Bouameur … Thomas M. Magin
    Studysummary This study found that epidermolysis bullosa simplex keratinocytes had impaired mitochondrial activity and more dispersed mitochondrial distribution compared to normal human keratinocytes.
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    Research cited in this study 3

    1. A Keratin Scaffold Regulates Epidermal Barrier Formation, Mitochondrial Lipid Composition, And Activity The Journal of Cell Biology · 2015
    2. Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice Journal of Biological Chemistry · 2014
    3. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013