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    Did you mean Mitochondrial DNA?
    GlossaryMitochondrial DNA

    genetic material in mitochondria inherited only from the mother

    Mitochondrial DNA (mtDNA) is the genetic material found in mitochondria, the energy-producing structures within cells. Unlike the DNA in the cell nucleus, mtDNA is inherited solely from the mother and is used to study maternal lineage and certain genetic disorders.

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community The mechanism of androgenic alopecia

      in Research/Science  31 upvotes 3 days ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 1 month ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.