A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians

    May 2012 in “ Genes & Development ”
    Danielle Wenemoser, Sylvain W. Lapan, Alex W. Wilkinson … Peter W. Reddien
    Studysummary This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.
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    Research cited in this study 3

    1. Wnt1/β-Catenin Injury Response Activates the Epicardium and Cardiac Fibroblasts to Promote Cardiac Repair The EMBO Journal · 2011
    2. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    3. Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis EMBO journal · 2001