A Study of Nexin 1 of Skin and Hair Follicle During Postnatal Development Period of Rat

    April 1998 in “ PubMed ”
    Minghao Xiang, Tzu‐Wei Yang
    TLDR Nexin 1 helps control hair growth in young rats.
    The study investigated the changes in Nexin 1 mRNA in the skin hair follicles of postnatal Wistar rats, aged 1 to 61 days, using radiolabel In Situ Hybridization. It was found that Nexin 1 mRNA signals appeared in follicular papillary cells at 4 days old, increased during the anagen phase, peaked in the middle-late stage, and disappeared in the catagen and telogen phases. Nexin 1 mRNA was not detected in other skin or hair follicle cells. The results suggested that Nexin 1, a serine-protease inhibitor, played a role in regulating hair follicle growth and cellular differentiation.
    Discuss this study in the Community →

    Related Community Posts Join

    2 / 2 results

      community 6 months on oral minox with no result

      in Minoxidil  10 upvotes 3 years ago
      A user who had taken oral minoxidil for 6 months without seeing any results and the advice given in response, which included trying microneedling in combination with topical minoxidil, as well as seeking a dermatologist's opinion.

      community Survived First Monte. Shedding is real

      in Progress Pictures  370 upvotes 1 year ago
      The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.

    Related Research

    6 / 6 results