Minoxidil Overdose: A Case Report and Review of the Literature

    June 2025 in “ Cureus ”
    Masakazu Kakurai, Yoshihiro Moriyama
    Studysummary This case report details a 61-year-old man's overdose on oral minoxidil, resulting in systemic side effects like hypotension and edema, which resolved without intervention; similar symptoms were observed in 14 other patients after minoxidil ingestion.
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    Research cited in this study 10

    1. A Very Bad Hair Day: Minoxidil Ingestion Causing Shock and Heart Failure Cureus · 2024
    2. Topical Minoxidil Overdose in a Young Man With Androgenetic Alopecia: A Case Report Curēus · 2024
    3. Minoxidil Overdose With Hypotension Effectively Managed With Norepinephrine, Rather Than Dopamine Clinical Toxicology · 2023
    4. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    5. Prolonged Hypotension Induced by Ingesting a Topical Minoxidil Solution: Analysis of Minoxidil and Its Metabolites Acute medicine & surgery · 2016
    6. Cardiovascular Effects of Ingesting Topical Minoxidil in Pediatric Patients Pediatric emergency care · 2014
    7. Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension Journal of Clinical Hypertension · 2004
    8. Overdose of Rogaine Extra Strength for Men Topical Minoxidil Preparation Journal of Toxicology Clinical Toxicology · 1999
    9. Minoxidil Overdose: Severe Hypotension and Tachycardia After Ingestion Chest · 1993
    10. Minoxidil Overdose With ECG Changes: Case Report and Review The Journal of emergency medicine · 1992

    Related research 1

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023