Study on Effect of Head, Tail, and Limbud Extracts of Mouse on Differentiation of Hair Follicle Stem Cells to Neural Cells

This study demonstrated that hair follicular stem cells from mature mice could be differentiated into neural cells using tissue extracts from 10-day-old mouse embryos. The extracts from the head, tail, and limbud were used at concentrations of 50% and 80% over a 2-week period. The results showed a significant increase in the neural cell marker β tubulin III, particularly in the group treated with the 80% concentration, indicating that higher concentrations of tissue extract were more effective in inducing differentiation. This suggested that the tissue extracts had a significant impact on the differentiation process of hair follicular stem cells into neural cells.