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Glossary Neural Stem Cells

specialized brain cells that can become various neural cell types

Neural Stem Cells (NSCs) are specialized cells in the brain and spinal cord that have the ability to develop into different types of neural cells, including neurons, astrocytes, and oligodendrocytes. They play a crucial role in brain development, repair, and regeneration, and are being studied for their potential in treating neurological disorders and injuries.

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Research

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research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins

106 citations , September 2010 in “Stem cells”

This study found that skin-derived precursor cells in mice can originate from both neural crest and somite lineages but show functional similarities regardless of their developmental origins.

research Neural Potential of a Stem Cell Population in the Hair Follicle

80 citations , September 2007 in “Cell Cycle”

This study found that nestin-expressing cells in the hair follicle bulge exhibit multipotent stem cell-like properties and can generate neural cells both in vitro and in vivo.

Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

research Combination of media, biomaterials and extracellular matrix proteins to enhance the differentiation of neural stem/precursor cells into neurons

25 citations , April 2012 in “Acta Biomaterialia”

This study observed that NSPC predominantly differentiated into neurons when exposed to serum fractions with molecules under 100 kDa, particularly with biomaterial and fibronectin, in the presence of basic fibroblast growth factor.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations , January 2014 in “BioMed research international”

In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.

research Sensory Reinnervation of Human Skin by Human Neural Stem Cell‒Derived Peripheral Neurons Ex Vivo

7 citations , July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study demonstrated that human skin can be efficiently reinnervated using human induced pluripotent stem cell-derived neural stem cells, promoting skin vitality and sensory reinnervation comparable to physiological conditions.

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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community Why does this industry still revolve around 5-AR inhibitors?

40 upvotes 5 years ago

Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.

community 24 years old, 6 month progress on once daily 1mg fin and twice daily topical minoxidil

in Progress Pictures 116 upvotes 1 year ago

A 24-year-old shared six months of progress using 1mg finasteride daily and topical minoxidil twice daily, reporting improved hairline and temples with no side effects. The user experienced initial shedding but noted significant regrowth and no erectile dysfunction issues.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 8 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community What’s the most effective way to beat Serb Derm?

in Treatment 7 upvotes 2 years ago

OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

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