Mixture of Mastic Gum and Peppermint Extracts Promotes Hair Growth and Health in Vitro and in C57BL/6 Mice

The study examined the effects of a mixture of mastic gum and peppermint extracts (FHH-MG) on hair growth and health, using both in vitro experiments and in vivo tests on 60 C57BL/6 mice. The mixture increased human dermal follicle papilla cell proliferation and showed anti-inflammatory and antioxidant properties. In mice, FHH-MG enhanced hair growth, gloss, and increased the expression of growth factors such as VEGF, EGF, β-catenin, and IGF-1, which are important for hair follicle development. The study suggests that FHH-MG could be a promising botanical alternative for promoting hair growth and health, although further research, including human clinical trials, is needed to confirm its efficacy and safety.