Minoxidil therapy in children with severe hypertension
May 1977
in “The Journal of Pediatrics”
TLDR Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
The study investigated the use of minoxidil therapy in six children with severe hypertension. The results showed that minoxidil is an effective antihypertensive agent, but the major side effect was fluid retention. Hirsutism was also observed in some patients. The authors recommended that minoxidil therapy should be limited to children with severe hypertension resistant to conventional, oral antihypertensive medications.
View this study on jpeds.com →
Cited in this study
research Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
research Minoxidil in refractory hypertension
Minoxidil effectively controls severe high blood pressure in children with few side effects.
research Control plasma renin activity and changes in sympathetic tone as determinants of minoxidil-induced increase in plasma renin activity.
Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
research Differential effects of propranolol on heart rate and plasma renin activity in patients treated with minoxidil
Propranolol affects heart rate and renin levels in minoxidil-treated patients.
research Minoxidil — An Alternative to Nephrectomy for Refractory Hypertension
Minoxidil effectively lowers blood pressure with few side effects.
research Minoxidil in severe hypertension with renal failure
Minoxidil effectively lowers blood pressure without major side effects.