TLDR Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
The study investigated the use of minoxidil therapy in six children with severe hypertension. The results showed that minoxidil is an effective antihypertensive agent, but the major side effect was fluid retention. Hirsutism was also observed in some patients. The authors recommended that minoxidil therapy should be limited to children with severe hypertension resistant to conventional, oral antihypertensive medications.
Cited in this study
6 / 6 results
55 citations
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October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
17 citations
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April 1975 in “The Journal of Pediatrics” Minoxidil effectively controls severe high blood pressure in children with few side effects.
57 citations
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February 1975 in “Journal of Clinical Investigation” Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
25 citations
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December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
180 citations
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July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
100 citations
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March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.