Minoxidil and Male-Pattern Alopecia: A Potential Role for a Local Regulator of Sebum Secretion with Vasoconstrictive Effects?

    November 1999 in “ Medical Hypotheses ”
    Sven Kurbel, Beatrica Kurbel, Dubravka Žanić-Matanić
    Studysummary Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
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    Research cited in this study 7

    1. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    2. Inhibitory Effects of bFGF, VEGF, and Minoxidil on Collagen Synthesis by Cultured Hair Dermal Papilla Cells Archives of Dermatological Research · 1996
    3. Effects of Hypertrichotic Agents on Follicular and Nonfollicular Cells In Vitro Skin Pharmacology and Physiology · 1996
    4. The Effect of Minoxidil Analogues and Metabolites on the Contraction of Collagen Lattices by Human Skin Fibroblasts British Journal of Plastic Surgery · 1995
    5. Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts Archives of Dermatological Research · 1995
    6. Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells Archives of Biochemistry and Biophysics · 1994
    7. Effect of Minoxidil Sulfate and Pinacidil on Single Potassium Channel Current in Cultured Human Outer Root Sheath Cells and Dermal Papilla Cells Journal of Dermatological Science · 1994