A Case Report of Microinfusion of Drugs Into the Skin (MMP®) With Minoxidil in Chronic Telogen Effluvium

September 2024 in “ Journal of Skin and Stem Cell ”

Adriana de Carvalho Corrêa, Carla Jorge Machado, Sueli Coelho da Silva Carneiro

minoxidil Microinfusion of drugs into the skin MMP chronic telogen effluvium Wnt signaling pathway growth factors Rogaine

TLDR MMP® with minoxidil may improve hair growth in chronic telogen effluvium.

This case report examines the use of Microinfusion of drugs into the skin (MMP®) with minoxidil for treating chronic telogen effluvium (CTE) in a 28-year-old female. Over three monthly sessions, MMP® with 0.5% minoxidil was applied to the right scalp, followed by daily 5% minoxidil application. Results showed a modest improvement in hair density, with an increase of 47 hairs in the parieto-vertex region. The treatment was well-tolerated, suggesting that MMP® may enhance minoxidil's effectiveness by activating growth factors and the Wnt signaling pathway. However, further research with larger, controlled trials is necessary to confirm its efficacy.

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Research cited in this study

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research Evaluation of the Safety and Efficacy of Platelet-Rich Plasma in the Treatment of Female Patients with Chronic Telogen Effluvium: A Randomized, Controlled, Double-Blind, Pilot Clinical Trial

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Platelet-rich plasma is a promising and safe treatment for increasing hair density and thickness in women with chronic telogen effluvium.

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research Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women

234 citations , December 1996 in “Journal of The American Academy of Dermatology”

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

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