TLDR Finasteride effectively blocks enzyme causing male pattern baldness.
This scientific paper from 1996 explores the mechanism by which finasteride inhibits human steroid 5α-reductase, an enzyme involved in the production of dihydrotestosterone (DHT), which is linked to male pattern baldness. The study found that finasteride acts as a potent bisubstrate analog inhibitor, forming a noncovalent complex with the enzyme that is irreversible and has a dissociation constant of K₁* ≤ 3 × 10-13 M. The study provides important insights into the mechanism of action of finasteride, which is commonly used to treat male pattern baldness and benign prostatic hyperplasia.View this study on pubs.acs.org →
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Finasteride effectively blocks enzyme causing male pattern baldness.