Human Melanocyte Development and Melanoma Dedifferentiation at Single Cell Resolution

May 2020 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

R.L. Belote, Daniel Le, Ashley Maynard, Ursula E. Lang, Adriane Sinclair, Vicente Planells-Palop, Laurence S. Baskin, Aaron D. Tward, Spyros Darmanis, Robert L. Judson‐Torres

melanocyte melanoma single-cell RNA sequencing epidermal melanocytes transcriptional programs dedifferentiation melanocyte biology

Studysummary This study identifies novel subpopulations of human epidermal melanocytes and specific transcriptional programs that differ from model organisms, providing insights into melanoma dedifferentiation.

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