Physiological Skin Oxygen Levels: An Important Criterion for Skin Cell Functionality and Therapeutic Approaches

    Nadira Chettouh-Hammas, Catherine Grillon
    Studysummary This review highlights that current in vitro models often fail to replicate the physiological oxygen levels experienced by different skin cell types, which could affect redox states and functions, potentially accelerating skin aging.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 4

    1. Improvement of Antioxidant Defenses in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models Oxidative Medicine and Cellular Longevity · 2023
    2. Dermal Papilla Cells and Melanocytes Response to Physiological Oxygen Levels Depends on Their Interactions Cell Proliferation · 2021
    3. A Perfusable Vascularized Full-Thickness Skin Model for Potential Topical and Systemic Applications Biofabrication · 2021
    4. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015