Improvement of Antioxidant Defenses in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models

    Nadira Chettouh-Hammas, Fabienne Fasani, Amandine Boileau … Catherine Grillon
    Studysummary This study reports that keratinocytes grown under low oxygen conditions (physioxia) demonstrated reduced reactive oxygen species production and increased antioxidant enzyme activity compared to those in higher oxygen conditions, highlighting the role of oxygen in regulating skin antioxidant defenses.
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    Research cited in this study 2

    1. Dermal Papilla Cells and Melanocytes Response to Physiological Oxygen Levels Depends on Their Interactions Cell Proliferation · 2021
    2. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015