November 2024 in “JAMA Dermatology” This consensus statement provides expert guidance on prescribing low-dose oral minoxidil for hair loss, noting a lack of representation of pediatric specialists and highlighting areas for future research.
48 citations
,
July 2023 in “Pediatric Dermatology” This study found that among adolescents with alopecia areata and significant hair loss, treatment with ritlecitinib resulted in greater hair regrowth and self-reported improvement compared to placebo over 48 weeks, with common side effects including headache, acne, and nasopharyngitis.
227 citations
,
April 2023 in “The Lancet” Ritlecitinib effectively treats alopecia areata and is well-tolerated.
5 citations
,
July 2020 in “Journal of the American Academy of Dermatology” This study suggests that using antihistamines alongside a regimen of topical corticosteroid and superficial cryotherapy may enhance hair regrowth in patients with mild to moderate alopecia areata.
6 citations
,
July 2019 in “Indian Journal of Dermatology” This study found that tinea capitis was the most common cause of scalp hair loss in children, affecting over half of cases, followed by alopecia areata, seborrheic dermatitis, and other conditions.
13 citations
,
April 2019 in “Seizure” This review found that valproic acid treatment significantly increases the risk of alopecia compared to other drugs, regardless of dose or treatment duration.
40 citations
,
September 2018 in “Journal of the American Academy of Dermatology” This letter discusses the emerging use of Janus kinase inhibitors, specifically oral tofacitinib, for treating alopecia areata in children, but reports no new clinical findings.
49 citations
,
May 2018 in “Journal of the American Academy of Dermatology” This letter discusses the limited treatment options for pediatric alopecia areata and the lack of controlled studies for therapies like systemic and off-label immunosuppressive drugs, without reporting new clinical results.
35 citations
,
October 2017 in “JAMA dermatology” This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.
40 citations
,
July 2017 in “Frontiers in Medicine” This review highlights that in children, hair loss can be attributed to diverse conditions like alopecia areata and tinea capitis, and stresses the importance of a holistic approach to diagnosis and management, including psychosocial support due to limited effective treatments.
22 citations
,
June 2017 in “Journal of dermatological treatment” This case series observed that 57% of pediatric patients with alopecia areata experienced significant hair regrowth with methotrexate treatment, which was generally safe, although some results were inconclusive due to follow-up issues.
4 citations
,
January 2017 in “Indian Dermatology Online Journal” This case study describes severe hypertrichosis in a 3-year-old with alopecia areata after unsupervised use of high-dose topical minoxidil, highlighting the need to avoid such practices in children.
139 citations
,
November 2016 in “Journal of the American Academy of Dermatology” In this retrospective review, tofacitinib treatment was associated with clinically significant hair regrowth in most adolescent patients with alopecia areata, though limitations suggest further studies are needed to confirm these findings.
11 citations
,
September 2015 in “Medical Principles and Practice” This study reported that hair and scalp disorders accounted for a significant portion of pediatric dermatology visits, with a diverse range of conditions observed among the children.
18 citations
,
March 2015 in “Journal of Dermatological Case Reports” This study identified distinctive trichoscopic features that may aid in diagnosing loose anagen hair syndrome, such as rectangular black granular structures, solitary yellow dots, and a predominance of follicular units with single hairs.
13 citations
,
March 2014 in “Pediatric Dermatology” This case report observed that a 2-year-old girl with loose anagen hair syndrome experienced rapid and significant improvement without adverse effects from tapered minoxidil 5% treatment over 28 months.
51 citations
,
January 2014 in “Pediatric Clinics of North America” This article examines various types of childhood alopecia and highlights the importance of identifying chronic conditions or those linked to underlying medical issues, but reports no new results.
32 citations
,
January 2014 in “Dermatology Research and Practice” This study found that trichoscopy can rapidly and noninvasively diagnose tinea capitis and alopecia areata in pediatric patients by identifying specific hair patterns associated with each condition.
17 citations
,
October 2013 in “F1000Research” This case report details a 2-year-old boy who developed generalized hypertrichosis after using 5% minoxidil foam for alopecia areata, highlighting the importance of caution and proper administration instructions for young children.
11 citations
,
January 2013 in “International Journal of Trichology” This report discusses a case of short anagen syndrome in a 3-year-old Hispanic girl and emphasizes its differentiation from loose anagen syndrome, without presenting new empirical findings.
30 citations
,
January 2013 in “International Journal of Trichology” This study found that in Jordanian children, tinea capitis, alopecia areata, and telogen effluvium were the most common causes of hair loss, with nutritional deficiencies such as iron and zinc deficiency also noted as significant factors.
37 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” This article discusses isotretinoin for severe acne vulgaris, noting its effectiveness but also highlighting significant side effects on skin, mucous membranes, and hair; it reports no new clinical results.
421 citations
,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
70 citations
,
April 2011 in “British journal of dermatology/British journal of dermatology, Supplement” This retrospective study found that methotrexate had variable efficacy in treating severe alopecia areata in children, with successful hair regrowth observed in five out of thirteen assessable cases.
15 citations
,
January 2011 in “Annals of Dermatology” This study found that neonatal occipital alopecia was associated with maternal age, delivery method, and gestational age, supporting the view that it is a physiological condition rather than an acquired alopecia.
28 citations
,
June 2010 in “Pediatric dermatology” This review discusses short anagen syndrome, highlighting its symptom of abnormally short scalp hair without associated systemic diseases, and notes that hair length often improves spontaneously after puberty without treatment.
56 citations
,
March 2010 in “Journal of Dermatology” This review provides a synopsis of 53 cases of temporal triangular alopecia, noting its frequent detection in early childhood and potential association with congenital diseases, but it reports no new clinical findings.
53 citations
,
March 2010 in “British Journal of Dermatology” This study found that androgenetic alopecia is the leading cause of hair loss in adolescents and may indicate endocrine disorders, emphasizing the need for accurate diagnosis.
46 citations
,
October 2009 in “Archives of Dermatology” This study found that loose anagen hair syndrome is a common form of alopecia in young girls, typically presenting with thin, sparse hair and usually confirmed by a hair-pull test.
79 citations
,
September 2009 in “Pediatric dermatology” This study found that the 308-nm Excimer laser was effective and safe for treating patchy alopecia areata in children, with hair regrowth observed in 60% of treated scalp patches.
150 citations
,
April 2008 in “Journal of The American Academy of Dermatology” This study found that videodermoscopy reveals distinct dermoscopic features in patients with alopecia areata incognita, aiding in biopsy decisions by identifying the appropriate sampling area and potentially avoiding unnecessary procedures.
34 citations
,
October 2007 in “International Journal of Dermatology” This study reported that the most common hair loss disorder among children in south-east Nigeria was tinea capitis, and its clinical course was influenced by parental attitudes towards treatment.
85 citations
,
April 2007 in “Dermatologic Clinics” This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.
58 citations
,
January 2007 in “Dermatology” Minoxidil use in children may cause heart issues.
72 citations
,
March 2005 in “British Journal of Dermatology” In this case series, researchers observed androgenetic alopecia in 20 prepubertal children with a strong genetic predisposition, despite the condition typically not occurring before puberty.
130 citations
,
January 2005 in “American Journal of Clinical Dermatology” This review discusses the dermatologic symptoms associated with severe eating disorders like anorexia nervosa and bulimia nervosa and how they can aid in early diagnosis, without reporting new results.
182 citations
,
October 2003 in “British Journal of Dermatology” These guidelines for alopecia areata management, prepared by the British Association of Dermatologists, provide evidence-based treatment recommendations and insights into the condition's epidemiology, diagnosis, and investigation.
146 citations
,
July 2003 in “Journal of the American Academy of Dermatology” In this study, clobetasol propionate 0.05% ointment was found to induce hair regrowth in 28.5% of patients with severe alopecia areata under occlusive conditions, though long-term benefit was limited to 17.8%.
42 citations
,
September 2000 in “British Journal of Dermatology” This report describes two children with congenital hypotrichosis and found their short hair is due to a shortened anagen phase, with the condition resolving spontaneously during puberty.
214 citations
,
March 1993 in “Archives of Dermatology” This article proposes five different mechanisms for telogen effluvium, supported by clinical findings, based on changes in different phases of the hair cycle.
55 citations
,
October 1992 in “Archives of Dermatology” In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
164 citations
,
November 1989 in “Clinical and Experimental Dermatology” This retrospective study found that juvenile alopecia areata is more severe and has a worse prognosis than maturity-onset alopecia areata.
104 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.