Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

    Erik J. Giltay, Louis Gooren
    Studysummary In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
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    Research cited in this study 11

    1. Objective Assessment of Treatment Response in Hirsutism Hormone research · 2008
    2. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999
    3. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    4. Comparison of a Gonadotropin-Releasing Hormone Agonist and a Low Dose Oral Contraceptive Given Alone or Together in the Treatment of Hirsutism The Journal of Clinical Endocrinology & Metabolism · 1995
    5. Leuprolide and Estrogen Versus Oral Contraceptive Pills for the Treatment of Hirsutism: A Prospective Randomized Study The Journal of Clinical Endocrinology & Metabolism · 1995
    6. Androgen Conjugates: Physiology and Clinical Significance Endocrine reviews · 1993
    7. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
    8. Correlation of Serum 3α-Androstanediol Glucuronide with Acne and Chest Hair Density in Men The Journal of Clinical Endocrinology & Metabolism · 1988
    9. Hair Growth and Androgen Responses in Hirsute Women Treated with Continuous Cyproterone Acetate and Cyclical Ethinyl Estradiol European journal of endocrinology · 1987
    10. Clinical Usefulness of Plasma Androstanediol Glucuronide Measurements in Women with Idiopathic Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1987
    11. 3 Alpha, 17 Beta-Androstanediol Glucuronide in Plasma: A Marker of Androgen Action in Idiopathic Hirsutism ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 1982

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