Is Hypercortisolism in Anorexia Nervosa Detectable Using Hair Samples?

December 2017 in “ Journal of Psychiatric Research ”

Franziska Ritschel, S. Clas, Daniel Geisler, Verena Haas, Maria Seidel, Julius Steding, Veit Roessner, Clemens Kirschbaum, Stefan Ehrlich

hypercortisolism anorexia nervosa hair cortisol concentration urine cortisol concentration cortisol hair follicles enzyme activity

Studysummary This study found that hair cortisol did not indicate expected hypercortisolism in acutely underweight anorexia nervosa patients and did not change significantly during short-term weight restoration.

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research Hair Cortisol Concentrations in Adolescent Girls With Anorexia Nervosa Are Lower Compared to Healthy and Psychiatric Controls

22 citations , August 2016 in “European Eating Disorders Review”

This study found that female patients with anorexia nervosa had lower hair cortisol concentration compared to healthy and psychiatric controls, which may be influenced by body mass index rather than anorexia-related endocrine changes.

research Correlation of Cortisol in 1-Cm Hair Segment with Salivary Cortisol in Humans: Hair Cortisol as an Endogenous Biomarker

80 citations , January 2011 in “Clinical Chemistry and Laboratory Medicine (CCLM)”

This study confirmed that the diffusion of cortisol from blood is a biologically endogenous source of hair cortisol, correlating significantly with salivary cortisol levels in healthy humans.

research Measurement of Cortisol in Human Hair as a Biomarker of Systemic Exposure

567 citations , October 2007 in “Clinical and investigative medicine”

This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.

research Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol

489 citations , June 2005 in “The FASEB Journal”

This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.

research Cutaneous Manifestations of Eating Disorders

48 citations , July 2002 in “Journal of Cutaneous Medicine and Surgery”

This review discusses the variety of skin conditions linked to eating disorders and emphasizes that resolving these skin issues often requires treating the underlying disorder.

research Cutaneous Manifestations of Eating Disorders

33 citations , April 2002 in “Journal of Cutaneous Medicine and Surgery”

This review discusses the skin conditions linked to eating disorders and emphasizes that treating the underlying disorder often improves these dermatological symptoms.