Industrial-scale processing of activated platelet-rich plasma from specific pathogen-free pigs and its effect on promoting human hair follicle dermal papilla cell cultivation
February 2017
in “Journal of The Taiwan Institute of Chemical Engineers”
TLDR Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
In 2017, a study was conducted to optimize the production of porcine platelet-rich plasma (PRP) and assess its effects on human follicle dermal papilla cells (HFDPCs), which are crucial for the hair growth cycle. The researchers developed a large-scale production process for porcine PRP, which was activated using a combination of collagen, thrombin, and calcium chloride. The study found that porcine PRP had higher growth factor levels than fetal bovine serum (FBS), a commonly used serum additive, and was stable during freeze-drying and surfactant treatments. HFDPCs treated with freshly prepared or freeze-dried PRP showed no significant difference in proliferation compared to FBS. The study concluded that porcine PRP is commercially viable as an FBS replacement and hair growth promoter.
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