Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

In 2012, a study investigated the effects of activated platelet-rich plasma (PRP) on hair growth. The researchers found that PRP increased the proliferation of dermal papilla (DP) cells, stimulated certain signaling pathways, and upregulated growth factors, all of which are potent stimuli for hair growth. In an in vivo study, mice injected with PRP showed faster hair growth cycle transitions compared to control mice. The study also found that PRP increased the expression of certain proteins in cultured human DP cells, suggesting it stimulates hair growth by inducing the differentiation of stem cells into hair follicle cells. However, further studies were needed to investigate the mechanism of action and safety of PRP before it could be applied clinically.