Heterozygous KRT32 Variant Is Responsible for Autosomal Dominant Loose Anagen Hair Syndrome

    May 2025
    Manuela A. Melo, Elizabeth Phillippi, Thomas O. Moninger … Hatem El‐Shanti
    Studysummary In this study, researchers identified the c.296C>T (p.T99I) variant in the KRT32 gene, which co-segregates with loose anagen hair syndrome, and found it decreases binding affinity to KRT82, potentially weakening hair anchorage.
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    Research cited in this study 14

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