Hematological and immune homeostasis of experimental animals under the influence of lotion, containing 5% minoxidil

December 2022 in “ Experimental and Clinical Physiology and Biochemistry ”

N.Ye. Chemodurova

minoxidil leukocyte eosinophils monocytes lymphocytes CD3 CD4 CD22 phagocytic activity Rogaine

TLDR A lotion with 5% minoxidil boosts the immune response in guinea pigs.

The study investigated the effects of a lotion containing 5% minoxidil on the immune system of guinea pigs. Significant changes were observed in the leukocyte blood count, including increases in eosinophils and monocytes, and a decrease in lymphocytes. The immune response showed a shift towards cells involved in hypersensitivity and immune-allergic reactions. Cellular immunity was enhanced, with increases in CD3, CD4, and CD22 cells, as well as phagocytic activity. These findings suggest that the lotion affects both cellular and humoral immunity, indicating a stimulation of the immune response in the experimental animals.

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Hematological and immune homeostasis of experimental animals under the influence of lotion, containing 5% minoxidil

Research cited in this study

research A Case of Contact Allergic Dermatitis to Topical Minoxidil

research An Overview of Herbal Alternatives in Androgenetic Alopecia

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research Minoxidil Use in Dermatology, Side Effects, and Recent Patents

research Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment

research Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia

research Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata

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