Hair regrowth in a male patient with extensive androgenetic alopecia on estrogen therapy
September 2012
in “Journal of The American Academy of Dermatology”
TLDR Estrogen therapy helped regrow hair in a bald man.
A male-to-female transsexual patient with extensive androgenetic alopecia (AGA) experienced full hair regrowth over completely alopecic scalp after being on estrogen therapy. The patient was also taking minoxidil, estrone, and Aldactone. The study suggests that adding estrogens to antiandrogen therapy may revitalize and maintain quiescent AGA hair follicles. The study also mentions that antimalarials are considered as systemic first-line treatment of cutaneous lupus erythematosus (CLE), while other medications, such as dapsone and retinoids, are among the second-line treatment options. One of the randomized controlled trials suggested that acitretin, an aromatic retinoid, may be as effective as hydroxychloroquine in the treatment of CLE.
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Cited in this study
research Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells
Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
research Medical treatments for male and female pattern hair loss
Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
research Androgenetic Alopecia
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research Treatment of female pattern hair loss with oral antiandrogens
Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
research Estrogens and the hair follicle. Ostrogene und der Haarfollikel
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
Related
research Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females
Topical estrogen helps hair growth in menopausal women with no major side effects.