TLDR Dupilumab can help regrow hair and improve skin conditions in patients with severe atopic dermatitis and alopecia areata.
A 46-year-old woman with severe atopic dermatitis and alopecia areata universalis experienced significant hair regrowth on her scalp, face, and lower legs after starting dupilumab therapy. Dupilumab, which blocks the IL-4 receptor α-subunit and reduces Th2 immune response, also alleviated her severe eczema and itching within 14 days, improving her sleep and quality of life without significant side effects. This suggests that patients with severe atopic dermatitis and alopecia areata may benefit from dupilumab treatment.
Cited in this study
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19 citations
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February 2019 in “JAAD case reports” A medication for skin rash also unexpectedly treated hair loss in a patient.
290 citations
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January 2018 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
148 citations
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March 2019 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
6 citations
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March 2019 in “JAAD case reports” A new mix of anthralin and calcipotriene might help treat severe hair loss.
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November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.