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An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity

research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity

April 2018 in “Journal of Investigative Dermatology”

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

research Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development.

2 citations , November 2004 in “Blood”

RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.

research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics

August 2024 in “International Journal of Molecular Sciences”

Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.

research Hair Eruption Initiates and Commensal Skin Microbiota Aggravate Adverse Events of Anti-EGFR Therapy

41 citations , December 2019 in “Science Translational Medicine”

Anti-EGFR therapy can cause skin issues, but FGF7 treatment might help.

research Hair Growth Under Dupilumab in Alopecia Areata Universalis and Atopic Dermatitis

1 citations , October 2021 in “Deleted Journal”

Dupilumab can help regrow hair and improve skin conditions in patients with severe atopic dermatitis and alopecia areata.

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community Fin/dut increase in estrogen and autoimmune diseases

in Chat 6 upvotes 2 years ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community 8 years of hair loss, turning 30 next month

in Progress Pictures 152 upvotes 4 months ago

The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 64 upvotes 5 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community When someone posts a scalp tension theory

in Satire 266 upvotes 4 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.