Improvement of Hair Damage by Lipophilic Vitamin C (Ascorbyl Tetraisopalmitate)

    Takeshi Misono, Shunsuke Yamaguchi, Satoru Hashimoto
    TLDR Lipophilic Vitamin C improves damaged hair texture and condition.
    The study investigated the effects of lipophilic Vitamin C (Ascorbyl Tetraisopalmitate, VC-IP) on damaged hair. It was hypothesized that VC-IP could react with amino groups in damaged hair, leading to improved hair texture. In vitro tests using amino-modified glass substrates showed that VC-IP had superior reactivity with amino groups compared to other oils. Application of a squalane solution containing VC-IP on damaged hair resulted in improved cuticle condition and increased water repellency. The research concluded that VC-IP not only served as a skin-whitening agent but also had the potential to improve damaged hair.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 30 results

      community Dr Kyle Gillett on topical Dutasteride

      in Finasteride/Dutasteride  56 upvotes 2 years ago
      The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  413 upvotes 7 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Possible solution: 2.5mg DUT for everyone

      in Chat  14 upvotes 7 months ago
      A user is experimenting with creating a DIY oral Dutasteride solution using raw powder, MCT oil, and Vitamin E to reduce costs. Others discuss their experiences with similar methods and the challenges of sourcing and testing Dutasteride.

      community My DHT levels while being on DUT for a year

      in Finasteride/Dutasteride  32 upvotes 5 months ago
      The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.

      community Oral Dut/Minoxidil for two years - no results.

      in Treatment  103 upvotes 2 months ago
      The user has used oral Dutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.

    Similar Research

    5 / 990 results