TLDR Gene regulation could revolutionize hair color by altering pigmentation from within.
The document explored the potential of using gene regulation to develop new hair coloring products that change hair color from the inside out. It focused on the role of melanin and genetic factors in hair pigmentation, and the use of nanocarriers for targeted delivery to hair follicles. The research suggested that understanding the molecular basis of hair greying could lead to effective antigreying cosmetics by activating melanocytes. It also discussed the use of small RNA oligonucleotides, such as siRNA, to regulate gene activity and alter hair color. The authors believed that advancements in understanding genetic mechanisms and delivery systems could revolutionize hair care by enabling genetic modulation of hair color.
20 citations,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
81 citations,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
94 citations,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
67 citations,
August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
8 citations,
September 2003 in “Journal of dermatological science” Substance P helps hair grow longer and faster.
15 citations,
April 2001 in “Journal of Dermatological Science” KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.