Classification and Management of Skin, Hair, Nail, and Mucosal Side Effects of Epidermal Growth Factor Receptor Inhibitors

    February 2007 in “ European journal of cancer ”
    A.F.S. Galimont-Collen, L.E. Vos, A.P.M. Lavrijsen … Hans Gelderblom
    Studysummary This review discusses the classification, pathogenesis, and management of skin, hair, nail, and mucosal changes due to EGFR inhibitors, emphasizing the importance of informing patients to improve therapy compliance.
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    Research cited in this study 4

    1. Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    2. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995
    3. Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin Journal of Investigative Dermatology · 1990
    4. Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition Journal of Investigative Dermatology · 1985