Cutaneous Side-Effects of EGFR Inhibitors and Their Management

January 2011 in “ PubMed ”

Laura Maximiliane Ehmann, Thomas Ruzicka, Andreas Wollenberg

EGFR inhibitors epidermal growth factor receptor cutaneous side-effects acneiform eruptions xerosis fissures paronychia changes in hair growth

TLDR EGFR inhibitors often cause skin issues like acne and dryness, which can be managed with specific treatments.

Epidermal growth factor receptor (EGFR) inhibitors were an important treatment for metastasized cancer, but they often caused cutaneous side-effects due to EGFR's role in skin and hair follicle health. Common early side-effects included acneiform eruptions, while xerosis and fissures appeared later. Paronychia and hair growth changes were less common and occurred after prolonged treatment. The document provided an overview of these side-effects and discussed therapeutic options for managing them.

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Research cited in this study

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