Cosmetic Effects of Anti-Epileptic Drugs (AEDs)
January 2024
in “
Authorea (Authorea)
”
New to Valproic acid? There is a guide in the encyclopedia. Read the guide → 
Studysummary This study found that Sudanese epilepsy patients prioritize medication intake despite cosmetic effects from antiepileptic drugs, which may be influenced by cultural perceptions unique to the population.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study on 420 Sudanese epilepsy patients over six months found that 20% experienced cosmetic side effects from antiepileptic drugs (AEDs), with hair loss being the most common among females taking sodium valproate (8.2%). Weight gain was also noted in 8.1% of patients on valproic acid. Other side effects included gingival hyperplasia, hirsutism, and acne in those taking phenytoin. Despite these effects, no significant correlation was found between cosmetic side effects and quality of life or medication adherence. However, a significant positive correlation was observed between the duration since the last seizure and quality of life (P=0.03). The study emphasizes the importance of considering cosmetic side effects, particularly for women, due to their impact on body image and self-esteem.
