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This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.

This report describes a 3-year-old boy with a potential new neurocutaneous syndrome characterized by unilateral alopecia, ipsilateral hemimegalencephaly, and intractable seizures.

In a rodent study, researchers found that oral phenytoin and spironolactone significantly mitigated 5-fluorouracil-induced hair loss and oxidative stress, suggesting potential therapeutic benefits for chemotherapy-induced alopecia and enhanced recovery.

This study found that Sudanese epilepsy patients prioritize medication intake despite cosmetic effects from antiepileptic drugs, which may be influenced by cultural perceptions unique to the population.

In this study, a literature review concluded that minoxidil is safe and effective for treating androgenetic alopecia, with few side effects, and highlighted the role of pharmacists in optimizing treatment by monitoring use and fostering adherence.